Per- and polyfluoroalkyl substances (PFAS) are a large class of synthetic chemicals widely used for their water-, oil-, and heat-resistant properties. However, their extreme environmental persistence and potential toxicity have triggered increasing regulatory scrutiny worldwide. This article reviews the current regulatory landscape, including developments in the European Union and the United States, and discusses the implications for industries transitioning toward PFAS-free supply chains.
Per- and polyfluoroalkyl substances represent a group of thousands of synthetic chemicals that have been widely used since the mid-20th century in consumer products and industrial applications due to their exceptional resistance to heat, water, and oil. Their chemical stability stems from strong carbon–fluorine bonds, which make them highly resistant to natural degradation processes. Because these substances can persist in the environment for decades—or even centuries—they are commonly referred to as "forever chemicals." This persistence allows PFAS to accumulate in soil, groundwater, wildlife, and the human body, raising serious environmental and health concerns. Research indicates that some PFAS compounds may cause reproductive toxicity, developmental effects, endocrine disruption, and certain cancers, while their mobility in water makes contamination difficult and costly to remediate.
Environmental persistence is one of the primary drivers behind regulatory initiatives targeting PFAS. Even if emissions were halted immediately, existing contamination would remain in ecosystems and drinking water for generations due to their extremely slow degradation. PFAS are released into the environment during manufacturing processes, through product use, and at the waste disposal stage, contributing to widespread contamination globally. Their ability to bioaccumulate in humans and animals has further intensified regulatory attention and public pressure for stricter controls on their production and use.
Several PFAS substances have already been restricted in the EU through both targeted substance bans and broader class-based restrictions. Notable examples include:
Future actions include the EU Packaging and Packaging Waste Regulation (PPWR), which mandates a ban on intentionally added PFAS in food-contact materials starting August 12, 2026, alongside proposals submitted under REACH that are currently under evaluation. The PPWR restricts PFAS to 25 ppb for a single compound or 250 ppb as a total sum of PFAS, with a 50 ppm limit for total fluorinated compounds, aiming to reduce health risks.
In 2023, Germany, Denmark, the Netherlands, Norway, and Sweden jointly submitted a proposal under the REACH regulation to restrict the manufacture, use, and placing on the market of thousands of PFAS substances across the EU. This proposal could potentially cover around 10,000 PFAS chemicals, although exemptions for essential uses may be considered where alternatives are not yet available. It is currently under evaluation by the European Chemicals Agency (ECHA), which must weigh environmental and health considerations against the significant economic implications for multiple industrial sectors.
In the United States, PFAS regulation has accelerated significantly in recent years. While there is no single federal ban covering PFAS in all consumer products, the U.S. Environmental Protection Agency (EPA) and the FDA have focused on drinking water standards and voluntary industry phase-outs for grease-proofing agents in food packaging.
More specifically, the EPA has introduced national drinking water standards for certain PFAS compounds, including strict limits of 4 parts per trillion (ppt) for the widely studied chemicals PFOA and PFOS. Additionally, under the Toxic Substances Control Act (TSCA), the EPA requires a one-time report from manufacturers and importers on PFAS use dating back to 2011, with most reporting deadlines falling in 2026. Separately, as of 2025, the FDA has declared that dozens of notifications for PFAS-containing grease-proofers are no longer effective, effectively ending their authorized use in the U.S. market.
Research regulations and material-related requirements affecting substances, materials, and engineering products.
In addition to federal actions, at least 14 U.S. states have implemented their own restrictions on intentionally added PFAS in food packaging, consumer goods, and/or textiles, including New York, California, and Washington. Other notable state-level actions include:
These evolving regulations are expected to significantly impact numerous industry sectors. Automotive, electronics, aerospace, and food packaging industries are particularly dependent on PFAS, which are used as coatings, lubricants, and barrier materials due to their durability and chemical resistance. The table below summarizes key sector-specific impacts.
Table 1. Impact of PFAS Regulations Across Key Industry Sectors
As regulatory pressure increases, a recent study conducted for the European Parliament's Committee on Industry, Research and Energy (ITRE) has highlighted the complex trade-offs between environmental regulation, industrial competitiveness, and technological innovation. The study's recommendations emphasize the need for careful, sector-specific actions rather than blanket restrictions. This adds complexity to chemical management efforts, as regulators increasingly favor class-based restrictions over substance-by-substance bans, making implementation more difficult for industry.
To support a smoother transition to PFAS-free supply chains, time-unlimited derogations have been advised for several critical industries, including aerospace, defense, and semiconductors. For other sectors, such as green and clean technologies, new time-limited derogations are needed to avoid disruptions to the development of emerging technologies.
As scientific understanding and regulatory efforts continue to evolve, PFAS regulation will likely remain one of the most significant chemical policy developments shaping industrial materials and chemical management over the coming decade.
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